Double Defense Heartworm Protocol is an approach that protects dogs from mosquitoes and heartworms.^1,2 This standard of care means that every dog should be on a macrocyclic lactone year-round and a mosquito repellent.

Groundbreaking studies by a third-party investigator, John McCall, MS, PhD, supports Double Defense in the fight against heartworms.

Phase one of the study proved that repelling and killing mosquitoes is effective in prohibiting microfilariae transmission from dogs to mosquitoes.²

Phase two of the study proved that dogs protected with Double Defense had no adult heartworms even using the JYD-34 strain of Dirofilaria immitis (one of the most resistant strains known).¹

In the studies using the Double Defense approach, there were:

• Fewer mosquito bites²
• Fewer infected dogs²
• No adult heartworms in dogs¹

You can give dogs comprehensive heartworm protection with Double Defense.

Learn more about Double Defense at fightheartwormnow.com.  

References

1. McCall, John W., Elizabeth Hodgkins, Marie Varloud, Abdel-Moneim Mansour, Utami DiCosty, Scott McCall, et al. 2016. “Blocking of the transmission of Dirofilaria immitis L3 (JYD-34 ML resistant strain) from infected mosquitoes to dogs and prevention of infection in dogs treated topically with dinotefuran-permethrin-pyriproxyfen and orally with milbemycin oxime alone or in combination.” Abstract presented at the meeting of the American Association of Veterinary Parasitologists, San Antonio, Texas.

2. McCall, John W., Elizabeth Hodgkins, Marie Varloud, Abdel-Moneim Mansour, Utami DiCosty. 2015. “Inhibition of the transmission of Dirofilaria immitis to mosquitoes by weekly exposure to microfilaremic dogs treated topically with dinotefuran–permethrin-pyriproxyfen.” Abstract presented at the meeting of the American Association of Veterinary Parasitologists, Boston, Massachusetts.