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Maropitantc is a central antiemetic indicated for the treatment of acute canine and feline vomiting, which is often a postsurgical sequela and a contributor to the pain burden. Maropitant works through a blockade of substance-P binding to the neurokinin-1 receptor, which is involved in pain processing. The true painmodifying effect of maropitant in dogs remains uncertain despite canine studies revealing an anesthetic-sparing effect and anoninferior effect to morphine in an ovariohysterectomy model.85,86

c Cerenia; Zoetis, Florham Park, NJ

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