Dogs 6 to 20 weeks of age

Applies to:

Dogs presented for initial vaccination that:
- Are late in starting the initial series
- Experience an extended interval (>6 wk) between doses during the initial series.

Click on a vaccine below for the recommendations:

Late starting the initial Series	Administer at least 2 sequential doses, 3 to 4 wk apart, until 16 to 20 wk of age to complete the initial series. A noncore vaccine when administered in combination with core vaccines requires 2 doses in the absence of Maternally Derived Antibody to immunize. (applies to both MLV and recombinant CDV vaccines)
>6 Weeks Interval Between Doses*	Administer sequential doses, 3 to 4 wk apart, with the last dose given at 16 or 20 wk of age. A noncore vaccine when administered in combination with core vaccines requires 2 doses in the absence of Maternally Derived Antibody to immunize. (Applies to both MLV and recombinant CDV vaccines) * The recommended MAXIMUM interval between doses (during the initial series) is 6 wk. Dogs exceeding 6 wk between doses during the initial series should complete the initial series in accordance with recommendations outlined in this column.

Late starting the initial Series	Administer a single dose (not earlier than 12 wk of age). Regardless of the dog’s age at the time the initial rabies vaccine dose is administered, a booster dose should be administered within 1 yr. (State/local/provincial statutes apply) NOTE: Some states specify a defined time during which the second dose of rabies vaccine must be administered.)
>6 Weeks Interval Between Doses	Not Applicable

Late starting the initial Series	Administer a single dose at presentation.
>6 Weeks Interval Between Doses*	Administer a single dose at presentation * The recommended MAXIMUM interval between doses (during the initial series) is 6 wk. Dogs exceeding 6 wk between doses during the initial series should complete the initial series in accordance with recommendations outlined in this column.

Late starting the initial Series	Administer a single dose at presentation.
>6 Weeks Interval Between Doses*	Administer a single dose at presentation. * The recommended MAXIMUM interval between doses (during the initial series) is 6 wk. Dogs exceeding 6 wk between doses during the initial series should complete the initial series in accordance with recommendations outlined in this column.

Late starting the initial Series	Administer 2 doses 3 to 4 wk apart. (NOTE: 2 consecutive doses are required to immunize.)
>6 Weeks Interval Between Doses	Published studies are not available. It is generally recommended to restart the 2-dose series when the vaccination interval between the first and second dose exceeds 6 wk.

Late starting the initial Series	Administer 2 doses 3 to 4 wk apart. (NOTE: 2 consecutive doses are required to immunize.)
>6 Weeks Interval Between Doses	Published studies are not available. It is generally recommended to restart the 2-dose series when the vaccination interval between the first and second dose exceeds 6 wk.

Late starting the initial Series	Administer 2 doses 3 to 4 wk apart. (NOTE: 2 consecutive doses are required to immunize.)
>6 Weeks Interval Between Doses	Published studies are not available. It is generally recommended to restart the 2-dose series when the vaccination interval between the first and second dose exceeds 6 wk.

Abbreviations

+ = “combined with” the vaccine that follows.
± = “with or without” the vaccine(s) that follow.
* The recommended MAXIMUM interval between doses (during the initial series) is 6 wk. Dogs exceeding 6 wk between doses during the initial series should complete the initial series in accordance with recommendations outlined in this column.
CAV, canine adenovirus-2;
CDV, canine distemper virus;
CPiV, canine parainfluenza virus;
CPV, canine parvovirus;
MLV, modified-live virus or attenuated.