Vaccination Recommendations for General Practice

For a printer-friendly PDF of these recommendations, click here.

For frequently asked questions and more information, click here.

NOTE: : Veterinarians have discretion to recommend administration of one or more Non-Core vaccines that may be considered regionally important for a majority of dogs

CORE in Blue

NONCORE in Light Gold

MLV or Recombinant Canine Distemper Virus, Adenovirus-2 and Parvovirus (DAPP), +/- Parainfluenza Virus
Rabies virus
Bordetella bronchiseptica + canine parainfluenza virus
Bordetella bronchiseptica only
Borrelia burgdorferi
Canine Influenza Virus-H3N8
Canine Influenza Virus-H3N2
Crotalus atrox


† CPV-2b and CPV-2c, field variants of canine parvovirus recognized in the United States today;
+ “combined with” the vaccine that follows;
± “with or without” the vaccine(s) that follow;
CAe, cellular antigen extract (Bordetella bronchiseptica);
CAV2, canine adenovirus-2;
CCV, canine coronavirus;
CDV, canine distemper virus;
CPiV, canine parainfluenza virus;
CPV, canine parvovirus;
CPV-2b and CPV-2c, field variants of canine parvovirus recognized in the US today;
FAVN, Fluorescent Antibody Virus Neutralization (Rabies);
RVNA, rabies virus neutralizing antibody;
IM, intramuscular;
IN, intranasal;
MDA, maternally derived antibody;
MLV, modified-live virus or attenuated;
oral, specifically administered into the buccal pouch (Bordetella bronchiseptica);
OspA, outer surface protein A (Borellia burgdorferi);
OspC, outer surface protein C (Borellia burgdorferi);
rCDV = recombinant canine distemper virus; SQ, subcutaneous

MEASLES VACCINE: Attenuated Measles Vaccine is a heterologous, single-dose (do not booster) vaccine for administration to young dogs (not less than 6 wk of age and not older than 12 wk of age) as a means of protecting young dogs (only) against canine distemper virus. The Measles vaccine must be administered by the intramuscular (IM) route.

NOTE: Canine coronavirus (CCV) vaccination is not recommended on the grounds that infection: (1) causes mild or subclinical disease, (2) generally occurs in dogs 6 wk of age and younger, and (3) is typically self-limiting.

NOTE: Administration of multiple doses of parenteral vaccine at the same appointment, particularly among small breed dogs (≤10 kg), may increase the risk of an acute-onset adverse reaction. Alternative vaccination schedules may be indicated, e.g., delaying administration of a noncore vaccine by 2 wk following administration of core vaccines.