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Ketamine

Ketamine exerts a pain-modifying effect via its N-methyl-Daspartate (NMDA) receptor antagonist actions. Subanesthetic ketamine constant rate infusion (CRI) in humans prevents pain and has antihyperalgesic, and antiallodynic effects.36,37Studies appear to support a similar clinical effect in dogs, although ketamine’s analgesic effect has not yet been studied in a feline surgical model.38–40 The International Veterinary Academy of Pain Management has adopted a position that the pain-modifying effects and safety profile of subanesthetic doses of ketamine warrant its use as part of a multimodal approach to transoperative pain management, especially in patients with risk factors that may predispose them to either exaggerated or maladaptive pain states

The information provided on this site is intended for your general knowledge only and is not a substitute for professional medical advice or treatment for specific medical conditions. You should not use this information to diagnose or treat your pet’s health problem or disease without consulting with a veterinarian. Please consult your veterinarian with any questions or concerns you may have regarding your pet’s condition.